Collagen is the primary component of the extracellular matrix in connective tissues and visceral organs, with the widest distribution in the skin, tendons, and bones. Structurally and genetically, collagen is classified into different types. Type I collagen, for instance, is composed of two α1 chains and one α2 chain, forming a heterotrimer approximately 300 nm in length. When used as a gel, collagen aids in the in vitro culture and enhances the expression of cell-specific morphology and functions. Collagen can also be utilized as a thin layer to promote cell attachment, with applications including the study of tumor cell invasion and migration, monocytic cell culture or differentiation research, and the radioautography of granulocytes and macrophages. Type I collagen is also employed in studies aimed at maintaining liver cell function, elevating differentiation status, and increasing the transcriptional levels of hepatic cell genes.
This product is sourced from the mouse tail and is dissolved in 0.02 M HAc solution. Its purity, determined by SDS-PAGE, exceeds 90%, and it is sterile.
Catalog Number |
C231102E/C231102S |
Specifications |
2 mL/10 mL |
Store at 4°C, valid for 1 year. Do not freeze.
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